This paper uses the functional approach to understanding networks to learn across several research policy networks in Peru. It considers the context and challenges they face as well as the various ways in which they have sought to overcome internal and external constraints to affect pro-poor policy changes. The paper finds that these networks carryout vary different strategies to research and communicate evidence; are organised around different structures; and address multiple policy issues. Based on their experience, the paper presents some of the best practices followed by the networks studies and puts forward a series of recommendations that attempt to bridge the knowledge gaps between them.